If Spain are going to stay close or be in any position to challenge for a win then it all comes down to the offensive production of Alba Torrens, who has averaged 16 points per game for the tournament.
United States' Kevin Durant, left, drives past Spain's Rudy Fernandez, right, during a semifinal round basketball game at the 2016 Summer Olympics in Rio de Janeiro, Brazil, Friday, Aug. 19, 2016. In the semifinals, Spain downed Serbia, 68-54. The penultimate round featured a rematch of the last two gold-medal games, as the reigning champion United States took on rival Spain.
Only the US men and India's male hockey players can claim such a run of domination in an Olympic team sport.
They've won the seven games in the Olympics by an average of almost 40 points and are putting up 102.3 points a contest - just a hair behind the record set by the '96 squad.
The Americans are overwhelming favourites to claim a 25th consecutive Olympic victory and third straight gold medal when they take on the victor of Australia and Serbia on Friday.
The Aussies lost 87-61 to Serbia in a Friday semi-final, scoring only 14 first-half points and never truly threatening.
"Based on this game and also the previous game against the United States, I think we can hope we are going to match up pretty good", said Serb centre Miroslav Raduljica. "We had the goal to win the gold medal but there is something more to it than that".
The Americans pulled away to win 118-107 in 2008 and held on for a 107-100 victory in London, but the defenses made their mark in this one. Spain has already guaranteed itself of a first-ever Olympic medal in women's basketball. "We don't want to leave with nothing less than a gold medal".
The last time the US failed to win gold at the Olympics came in 2004 when they fell to eventual champion Argentina in the semifinals and had to settle for bronze.
Los Angeles Clippers center DeAndre Jordan was the biggest contributor on the boards for the United States, finishing with 13 rebounds.
While Kevin Durant's 14 points were important, it was Jordan who played co-star to Thompson in this game. Anything but a USA win-and a comfortable one at that-would be a shock.
"We've got one game, and that's what we came here for", he said. They trailed by as many as 31 points midway through the fourth.
Gasol said after he believed Spain missed its best chance to beat the United States.
"I'm always looking forward to playing for the national team".
It was basketbrawl at its best - a "hard" game, Krzyzewski called it - with players diving for loose balls and often two or three of them sprawled on the court under the rim after a shot went up.
That sets up a rematch of the 2014 World Cup final between the USA and Serbia.