The automaker said it's eliminating the third shift at a factory in Lansing, Michigan, that makes the Camaro and another in Lordstown, Ohio, where GM builds the Cruze.
The shifts will end in January, GM said.
A similar suspension will go into effect at the Lansing Grand River plant in MI.
GM said the job losses will hit 1,200 factory workers in OH and 800 in MI, though some of those workers may be offered other positions.
General Motors Company (NYSE:GM) plans to lay off 2,000 employees at two US auto plants, one in OH and one in MI by early 2017. The company plans to spend $668 million on the Toledo plant, $211 million at the Lansing facility, and $37 million in Indiana.
Lordstown Assembly in Lordstown, Ohio, makes the compact Chevrolet Cruze sedan.
In contrast to its planned cuts, GM also announced it would invest more than $900 million in three facilities - Toledo Transmission Operations in Ohio, Lansing Grand River in MI and Bedford Casting Operations in IN - to prepare the facilities for future product programs.
New U.S. vehicle sales are down 0.3% year over year through October and passenger cars have been particularly hard hit, with sales down almost 10%.
The Lansing Grand River plant builds the Cadillac ATS and CTS, whose sales were down 17 percent through October.
The Lordstown plant now employs 4,500 people. GM's auto sales were reported down 7.5% at the end of last month. It employs about 2,700 workers now; 839 of them will be cut. Camaro sales are down 9 percent through October.
General Motors plans to lay off 2,000 employees at two US auto plants in early 2017, the automaker said on Wednesday.
President-elect Donald Trump has repeatedly told automakers that, if elected, he intends to impose a 35% tax on cars they build in Mexico for the USA market. The exact number of layoffs could still fluctuate, GM says, depending on how many people decide to retire or leave the company prior to layoffs in January. It has been relatively quiet about what vehicles and engines it will build in Mexico, though some analysts believe some next-generation Chevrolet Equinox and GMC Terrain small crossover production will shift from Canada to Mexico.