"Regime change is something that we think is going to happen", she said, adding that Washington was also focused on fighting the Islamic State of Iraq and the Levant (ISIL) in Syria and ending Iranian influence.
US forces struck a Syrian airfield Thursday in response to the Syrian government's chemical weapons attack April 4, 2017, in Khan Sheikhoun, which killed or injured hundreds of Syrians.
Administration officials insisted Friday that their overall policy hadn't changed and that the strike was only meant to convey that chemical weapons are unacceptable.
Before Donald Trump's shock U-turn approval of airstrikes on Syria, the US, UK and France had brought a resolution before the United Nations Security Council demanding an investigation into the attack, which is believed to have killed at least 72 people, including 20 children. He called the Assad government a main force against terrorism and said it deserved the presumption of innocence in the chemical weapons attack.
"It was a very deliberate, very proportional, and very targeted strike undertaken in response to the chemical weapons attack".
The Syrian government has strongly denied responsibility and says it does not use chemical weapons.
Speaking at a press conference earlier this week, Johnson said: 'We in the United Kingdom, together with our French friends, have called an emergency meeting of the UN Security Council.
But the facts concerning the suspected use of chemical weapons have yet to be fully clarified.
Trump's actions in Syria could signal to China that the new president isn't afraid of unilateral military steps, even if key nations like China are standing in the way.
G7 foreign ministers were to send a "clear and coordinated message" to Russian Federation over its stance on Syria as the U.S. ratcheted up the pressure following a suspected chemical attack in the war-torn country. The worldwide outcry fueled an emotional response from Trump, who appeared to abandon his much-touted "America First" vision for a stance of humanitarian intervention, akin to that of previous American leaders.
USA officials placed some of the blame on Russian Federation, one of Syria's most important benefactors.
He said: "It actually shows that the world's most powerful country and most economically successful country is willing to show a bit of leadership.Diplomacy is always better when it is backed up by strength". Under Obama, the United States largely pulled back from its support for so-called "moderate" rebels when Russia's military intervention in September 2015 led them to suffer a series of battlefield defeats.
The army chiefs of Russian Federation and Iran discussed the United States strikes in Syria by phone on Saturday and vowed to continue the fight against "terrorists" and their supporters, Iranian media reported. "What America waged in an aggression on Syria is a crossing of red lines".
The Local Coordination Committees, another monitoring group, said the airstrike was carried out by Russian warplane.
An attack on a rebel-held area in northwestern parts of Syria killed more than 100 people, including children.