The region where the strike took place, the restive Achin district, has for almost two years been the site of fierce fighting between the local Islamic State affiliate, known as Khorasan Province, and U.S and Afghan forces.
On Thursday evening, the USA military dropped a GBU-43 or Massive Ordnance Air Blast (MOAB) bomb, the largest non-nuclear bomb, on an IS cave complex in Achin District, eastern Nangahar Province bordering Pakistan.
In another dramatic show of military force after the bombing of a Syrian airfield with 59 Tomahawk missiles, the USA military yesterday dropped a GBU-43/B, colloquially known as the "Mother Of All Bombs" or MOAB, to target tunnels and bunkers built by Islamic State fighter in Nangarhar province.
The security situation remains precarious in Afghanistan, with a number of militant groups trying to claim territory more than 15 years after the USA invasion which toppled the Taliban government.
The Islamic State group denied on Friday it had suffered casualties from the U.S. military's largest non-nuclear bomb which hit its mountain hideouts in Afghanistan, in a statement on its propaganda agency Amaq. That apparently reflects President Donald Trump's vow for a more aggressive campaign against the group. Officially known as a GBU-43B, or massive ordnance air blast weapon, the MOAB unleashes 11 tons of explosives.
The Pentagon released a video of the strike Friday. Agricultural terrasses are visible in the footage, but no population centers.
The Afghan Defence Ministry said in a statement that the bomb destroyed several IS caves and ammunition caches.
Those in favor of the attack said the MOAB was the only way to dismantle the cave complex, landmines and tunnels.
The Islamic State group has denied suffering any casualties, issuing a statement through its propaganda agency Amaq, saying: "Security source to Amaq agency denies any dead or wounded from yesterday's American strike in Nangarhar using a GBU-43/B".
Waziri noted that the fortress contained tunnels more than 12o feet deep into the ground.
The commander of US forces in Afghanistan, Gen. John Nicholson, said in a statement Thursday that it was the "right munition" to use to destroy the militants' network of tunnels in the area.
He said civilians suffered no casualties in the attack.
"This is the right weapon against this target".
We have the greatest military in the world and they have done a job as usual.
Pakistani villagers living near the frontier said the explosion was so loud they thought a bomb had been dropped in their village by USA warplanes targeting militants in Pakistan.
"The earth felt like a boat in a storm", one villager who lived near the blast told The Guardian. He later went near the border, where he met with other residents.
"If you look at what's happened over the last eight weeks and compare it to, really, what's happened over the last eight years, you'll see there's a tremendous difference, tremendous difference", Mr. Trump said.
Nangarhar's Achin district is the birthplace of Islamic State in Afghanistan.
"I thought my house was being bombed".
Residents in Afghan villages near the target area felt Thursday's powerful strike.
"They killed our women, youths and elders, sitting them on mines", Hakim added. "So, we have given them total authorization".
The US estimates 600-800 IS fighters are in Afghanistan, mostly in Nangarhar. It's the term militants use for the area they want to fully control in that region, composed of former members of the Afghan and Pakistani Taliban.
Thursday's strike came as US President Donald Trump dispatches his first high-level delegation to Kabul, amid uncertainty about his plans for the almost 9,000 American troops stationed in Afghanistan.
Nangarhar provincial spokesman, Attaullah Khogyani, gave a toll of 90.
Currently, there have been no reported civilian deaths resulting from the bombing. He said a clearance operation to assess the site of the attack was continuing.
Daesh is the Arabic acronym for Islamic State. The two militant movements are rivals of each other.
The US military has dropped an enormous bomb in Afghanistan, according to four US military officials with direct knowledge of the mission.