Spurs boss Mauricio Pochettino said over the weekend that he was optimistic the prolific 24-year would get the green light to face the Spanish giants.
We are confident that he can play but I cannot say 100% until tomorrow. "We're feeling good and we're thinking about the game".
"The important thing is we don't dwell on that".
Isco picked up a thigh muscle injury late in that game and will be monitored ahead of the clash, with Marco Asensio and Lucas Vazquez ready to step in if he does not make it.
"Yes, we are going to be fearless". There is always pressure, but despite that we're not going to lose our heads. We can only analyse the game they have played in the Champions League and 15 days ago in the Bernabéu.
Liverpool are expected to boost their chances of progressing when they host rank outsiders Maribor, while Charlie's former club Celtic need to beat Bayern Munich to keep their chances of progressing alive. "It was a great night, a great game to watch as a Spurs fan, so fingers crossed we can get the same sort of result". It's not just me saying that, the results speak for themselves.
Asked to explain his side's problems, Madrid defender Marcelo claimed a lack of motivation for the more mundane La Liga fixtures might be to blame. Some teams play five, some teams play four, some teams play three. There could be a surprise.
Madrid can book their place in the last-16 with a win in north-west London and they'll be looking to bounce back after a defeat on Sunday. Sometimes, it is better to play them after a loss and sometimes they can be relaxed and confidenct.
"As for me, I played in the old Wembley and that was a great feeling".
"I'm happy because we have one player more to help the team what we want to achieve, to reach the next stage of the Champions League".