Trump did not indicate what set him off, but Clinton recently challenged the legitimacy of his election in 2016 because of evidence of Russian interference in the campaign via hacked emails and "fake news".
In a tweet Saturday morning, Trump told the 2016 popular vote victor to "get on with your life" but urged her to "give it another try in three years".
Just before his tweets on Clinton, Trump announced that he would be putting the decision to remove restrictions on importing African elephant trophies from Zimbabwe and Zambia on hold.
Trump lashed out at his former rival on Saturday, calling called Clinton "the worst (and biggest) loser of all time", after the ex-Democratic nominee made pointed criticisms in a series of interviews about Trump's political and moral legitimacy.
She also called for investigations into the elections to continue.
"President Trump and I have talked and both believe that conservation and healthy herds are critical".
When asked by host Rita Cosby if there is anything she admires about President Trump or what he's accomplished while in office, she quickly answered, "No".
"Donald Trump refused to say that he'd respect the results of this election", Clinton tweeted in October of past year.
"I don't hear that from Roy Moore or Donald Trump", Clinton said, referring to the two men not being accountable for their own actions, while Sen.
The President often takes to Twitter to assail his former political opponent and paint her and Democrats as the "real Russian Federation story".
She also singled out Wisconsin, a state she lost, and accused Republicans there of voter suppression through things like voter ID laws, which require voters to show identification to vote.