It will be the final game of pre-season for both sides, with Chelsea slated to face Manchester City in the Community Shield at Wembley four days later. Games against newly-promoted trio Wolves, Cardiff and Fulham are part of a sequence which also includes Huddersfield, Newcastle and Brighton - the three teams who came up the previous season.
Manchester United fans have reacted positively to the announcement of the fixtures and believe their side have been handed a boost in their bid to win the Premier League this season with a comfortable looking start and end to the campaign.
Liverpool's start appears more challenging.
They will be hosting Huddersfield on Boxing Day before travelling to Newcastle United on New Year's Day.
The redeveloped White Hart Lane will not be ready for the start of the season, so their first home game against the Cottagers will be played at the national stadium.
Fulham begin with London derbies against Crystal Palace and Tottenham, while Cardiff follow their opener at Bournemouth with a home game against Newcastle. After the Gunners host the champions, the team now managed by Emery are at Chelsea.
Absolutely, it is the game before the season starts.
The opening round of Premier League fixtures is completed by Southampton's clash with Burnley at St Mary's and Watford taking on Brighton & Hove Albion at Vicarage Road.
The first Manchester derby, which will pit last season's top two against each other, is due to take place on November 10 when Jose Mourinho's United make the short jounrey across town.