Here's all the results and highlights from today's play.
She next faces Italy's Camila Giorgi who saved a match point to beat Katerina Siniakova of the Czech Republic 3-6, 7-6 (8/6), 6-2.
"It's good fun that it's different but it would be nice to add a splash of colour, let's just be honest for a second here", said the 36-year-old.
"In the past it has made me nervous when I've seen bigger guys go out". I am playing well.
"I had my chances to win here a few years ago".
"It's true, I favoured him in that section together with maybe (Milos) Raonic".
At this year's tournament, Australia's John Millman became the latest player to be ensnared by the underwear police when his choice was deemed to be too colourful.
The Greek was a straight-sets victor against Thomas Fabbiano, triumphing 6-2 6-1 6-4. Another statistic that makes this one seem like quite a mismatch: Federer is 5-0 against Mannarino, winning 12 of the 13 sets they've played.
There was no comparable follow-up to Pella's giant-killing as he was beaten in straight sets by world number 103 Mackenzie McDonald. The match is scheduled to conclude on Saturday.
If Williams passes the test delivered by Pliskova, a rematch of the 2016 Wimbledon women's final awaits against Kerber, who beat Williams for her first major crown at the 2016 Australian Open.
The eight-time champion will face French 22nd seed Adrian Mannarino on Monday for a place in the quarter-finals.
The 36-year-old faces Russian qualifier - and fellow mother - Evgeniya Rodina in the last 16.
"This is only my second serious tournament back", Williams, who is returning from a maternity leave, said.
"Of course, 2008 was a very important moment for me when I achieved the world No. 1 for the first time in my career because in some way I felt that I deserved it", he explained.
Golovin's post-match press conference featured 15 questions, 10 of which concerned her flame-red under-garments.
It's the first time in the Open era that none of the top five women's seeds have made the last 16 of a Slam.
No. 9 seed Williams lost to No. 20 Kiki Bertens of the Netherlands 6-2, 6-7 (5), 8-6 in the third round.
"Just ran out of time in the end, " Venus said. I honestly think he can cause some damage the next round.
Williams is the fourth former women's champion to get knocked out, joining Maria Sharapova, Petra Kvitova and last year's victor Garbine Muguruza.
Fourth-seeded Alexander Zverev reached the third round in the men's event by beating Taylor Fritz of the US 6-4, 5-7, 6-7 (0), 6-1, 6-2 in a match that was suspended a day earlier after the third set. She plays Kiki Bertens first-up on No 2 Court, the victor advancing to the quarter-finals against either Julia Görges or Donna Vekic.