I'm a big player, big serve.
(25) Serena Williams bt.
Beaten by Serena in the 2016 final, Kerber takes on Russian 14th seed Daria Kasatkina, a 6-7 (6/8), 6-3, 6-2 victor against Belgian world number 47 Alison Van Uytvanck.
"I'm more concerned the World Cup final will have issues because the Wimbledon final is going on", said the eight-time champion after seeing off France's Adrian Mannarino in straight sets on Monday. He went on to cement his own legendary status with a supreme 2015 showing, which ended with an 80-6 record and featured a second successive Wimbledon final win over Federer, before he "completed" tennis a year later when a French Open success delivered a career Grand Slam.
But first they have to negotiate their quarter-final matches on Wednesday.
Raonic has the greater experience at Wimbledon, however, reaching at least the last eight in four of his past five appearances here - including a run to the 2016 final where he was beaten by home favourite Andy Murray.
Three times he was scheduled last on court, putting him at risk of falling victim to fading light with the burden of having to return the following day.
In a match suspended from Monday night due to darkness with the Argentine star two sets to one ahead, Del Potro sealed victory on a fifth match point after nearly four and a half hours of action on Court Two. Del Potro leads Simon 7-6 (1), 7-6 (5), 5-7, 0-0.
With world number one Rafael Nadal waiting for the victor, Tuesday's fourth set, played in much cooler conditions than the first three the day before, turned into a mini-epic before Del Potro eventually prevailed 7-6 (1) 7-6 (5) 5-7 7-6 (5).
Eight-time champion Federer will be playing in his 53rd Grand Slam last-8 when he tackles either Gael Monfils of France or Kevin Anderson, the 8th-seeded South African. "I feel like the more experienced you are, the more you can deal with those better". The Spaniard is hoping his old rival, and eight-time champion, gets knocked out before that.
It all began with the official Twitter account of Wimbledon posting a video of Federer in action, with him playing what looks like a forward defensive stroke.
Federer, sublime so far, will be a step up but Anderson is making all the right noises as he prepares for arguably the biggest challenge in tennis.
Scheduled last on No. 1 Court, Djokovic and Khachanov did not get underway until after 19:00 local time at the All England Club on Monday.
(11) Angelique Kerber bt.
Nadal, who plays at a slower, more deliberate pace, had no trouble with 93rd-ranked Jiri Vesely either, dismissing him, 6-3, 6-3, 6-4, in less than two hours. "It was dark so I couldn't see the ball that well and it was very windy".
Djokovic had to play that fourth round match on the Tuesday and quarter-final on the Wednesday, when he was forced to retire against Tomas Berdych with an elbow injury.