According to a doctor at Al Thawra Hospital many injured have been transferred to other hospitals and "there is a large number of deaths, and we can not count now because the number is large, above the capacity of the hospital".
Medical officials and the United States blame the Saudi-led coalition, which in turn pins responsibility on the Iran-backed Houthi rebels. "The Houthi militia are behind killing of civilians in Hodeidah", Col.
Strikes have picked up around the city since the Saudis last week accused the Iran-aligned Houthis of attacking two oil tankers operated by one of the kingdom's companies in the waters of the Red Sea.
Yemen's government maintains the rebels' "unconditional withdrawal" from Hodeida is key to restarting the talks.
"There is a pond of blood outside the hospital's building", he said.
The Yemen conflict was sparked by the Shia-led Houthi rebels taking control of Yemen's capital Sanaa in 2014, which sent the internationally recognized government of Abdrabbuh Mansur Hadi fleeing to exile.
The strikes hit a fish market and the entrance to a nearby hospital, eyewitnesses and medics said.
Speaking to members of the UN Security Council, Griffiths said that "a political solution" to bring an end to the war in this country is "available", and urged world leaders to support this new push for peace negotiations.
"We apply the highest global standards in targeting operations in Yemen", he said.
"You have heard the statistics many times: more than 22 million people - 75 per cent of the population - require humanitarian assistance and protection".
United Nations special envoy Martin Griffiths has held talks with both sides in recent weeks in hopes of preventing a full-scale coalition assault on Hodeida.
"With the economy in tatters and health and sanitation facilities throughout the country destroyed, conditions are now rampant for disease and starvation to spread", said Tamer Kirolos, Save the Children's Yemen Country Director.