He said any doubts he had about the potential importance of uterus transplants were erased after meeting the mother of the first baby born after a live donor uterus transplant.
The healthy baby girl was delivered last December to a 32-year-old woman who wasn't born with a uterus. Seven months after the operation, with no indications of rejection or abnormalities, and menstruation appearing regular, the recipient received one of her embryos.
The first baby has been born using the transplanted womb from a dead woman, and British doctors say they are planning to replicate the procedure in the UK. But all of the other successful deliveries so far have been made possible by living donors - often women who opt to donate their uterus to a close friend or family member without one.
The U.S. had its first uterine transplant in 2016, but the recipient had to have it removed days later due to a fungal infection, according to a report in the Cleveland Plain Dealer.
However, he cautioned: "Uterine transplantation is a novel technique and should be regarded as experimental".
Surgeons spent 10.5 hours plumbing in the organ by connecting veins, arteries, ligaments and vaginal canals.
The transplanted uterus was removed during the C-section, allowing the woman to stop taking the immunosuppressive drugs.
"This is a great alternative compared to live donor uterus transplants and therefore a really historic achievement", said Dr. Tullius, who is also a professor of surgery at Harvard University.
Besides saving the life of patients with failed vital organs, scientists have also conducted hand or face transplants in recent years to improve a person's quality of life.
Although uterus transplants are a growing area of medicine, they remain highly experimental and are very hard surgeries to complete.
These are still early days for uterine transplants, says Kate O'Neill, co-lead investigator for the University of Pennsylvania's uterus transplant program, who was not part of the work in Brazil.
The mother and baby were discharged from the hospital three days after birth. Falcone said the fact that the transplant was successful after the uterus was preserved in ice for almost eight hours demonstrated how resilient the uterus is.
Study authors wrote that, "the success expands prospects for childbirth among women with infertility attributable to uterine factors".
In December 2017, doctors at Baylor University Medical Center in Texas announced that the first US baby was born to a mother who received a uterus transplant from a living donor.
"The numbers of people willing and committed to donate organs upon their own deaths are far larger than those of live donors, offering a much wider potential donor population", he said.
The fertilised eggs were implanted after seven months. Previously, uterus transplants from a live woman were the only option, but donors are in short supply.