With everyone seated, the presenters opened the show with a monologue where Oh highlighted the importance and significance of the box office smash Crazy Rich Asians, which featured an all Asian cast.
Stone, who played Allison Ng in the latter comedy (a character who was part Chinese and Hawaiian) could be heard off-screen shouting "I'm sorry".
Host Sandra Oh was praising the hit 2018 film "Crazy Rich Asians" for being the "first studio film with an Asian-American lead since "Ghost in the Shell" and 'Aloha'".
"I said yes to the fear of being on this stage tonight to look out onto this audience and witness this moment of change", Oh said.
In addition to Aloha, Ghost in the Shell was criticized for casting Scarlett Johansson as its lead character, a Japanese fighter named Major Mila Killian.
"I've learned on a macro level about the insane history of whitewashing in Hollywood and how prevalent the problem truly is", Stone told News.com.au, while promoting Irrational Man.
The apology from Stone was not captured on cameras so it was hard to tell where it came from at first, but those in the crowd confirmed it came from the actress at her table. "It's ignited a conversation that's very important".
The camera didn't cut to her, which perhaps adds to the notion that this apology was unplanned, and that Emma really, really means it.
Many believe it was Emma Stone, who controversially played a woman of Asian descent in 2015's "Aloha".