The former "Suits" actress will take over two patronages from the queen, including the National Theatre (a flawless match for the former Hollywood star) and the Association of Commonwealth Universities, which offers scholarships and "life-changing educational opportunities", Kensington Palace said in a statement.
But it appears Meghan found a clever way to control her nerves and feel more confident, which she shared with representatives of Smart Works, a charity of which she is now patron.
Meghan will have an affinity with the National theatre after spending a decade working in television where she was best known for her role in the hit United States legal drama series Suits, playing paralegal-turned-lawyer Rachel Zane.
Rufus Norris, director of the National Theatre said: "I would like to thank The Queen for Her Majesty's long and unwavering support and service to the National Theatre".
However now a source said to be close to the royal household has slammed the rumours, revealing that staff are "excited" by her enthusiasm, and describing her management style as "very different" to that of her sister-in-law Kate Middleton. The organisation helps women get into or get back into the workforce.
Markle continues sharing her passion for the arts, access to education, and animal welfare through her work as a duchess. "Mayhew works to improve the lives of dogs, cats and the people in our community".
Other reports claimed that Prince Harry's wife was responsible for three royal aides quitting, after she "shook up the household with 5am emails".
Royal patronages are not necessarily for life and the younger royals usually have fewer patronages than older royals, as they steadily acquire more. "She's the type of person who is best friends with her stylist", the source added.
The announcement of Meghan's official patronages comes as she prepares for a busy 2019.
The couple are awaiting renovations to be completed on their new home, "Apartment 1" at Kensington Palace - technically a wing of the palace with 21 rooms and adjoining doors to "Apartment 1A" (which belongs to Will and Kate).