"Watford play again, against Fulham on Tuesday, before they face Wolves at Wembley but I don't think Gracia will play his best XI at Old Trafford".
"I think they are fresh mentally and in the legs and we are going to try", Guardiola said according to Goal.
Silva opened the scoring early for City at Craven Cottage, before setting up Sergio Aguero for the second in a comfortable win for Pep Guardiola's side. This game was tricky - 12:30 on a Saturday, a sunny day.
"We have a tough, tough opponent".
Fulham, by contrast, remain 13 points adrift of safety with just 18 left to play for and failed to register a single shot on target at home for the first time in nine years.
"While it's still mathematically possible we won't give up, but I'm a realist and we all understand the predicament ahead".
Former Ireland striker Tony Cascarino is expecting Liverpool to drop points against mid-table sides, which he believes will cost them the title at the end of the season. "The main focus in the last six games is to keep pushing and end the season on a positive in a disappointing campaign".
In a depressingly dismal season for Fulham, an upset victory over Manchester City would provide a welcome boost after so many close calls against the Premier League giants. Fulham tomorrow and win the game.
Aguero was withdrawn before the hour as City coasted through the second half, leaving manager Guardiola to downplay any injury issues around the Argentina hitman.
It is little wonder Fulham is next-from-last and facing relegation given the sloppiness of the defending before both City goals.
Still, City, who have won the League Cup and are in the FA Cup semi-finals and Champions League quarter-finals, moved closer to an unprecedented, if still unlikely, feat with 14 matches left.
With City firmly in control, Aguero was replaced by Gabriel Jesus after 57 minutes and Guardiola confirmed the switch was made only as a precaution. "As a precaution he chose to not continue and hopefully will not be a bit issue", Guardiola added.