Mir Ziaullah Langau, the provincial home minister, said the suicide bomber had walked up to the marketplace and killed both Shiites and Sunnis.
Shortly after the attack, the Hazara community members including women and children staged a sit-in which continued on Saturday, demanding better security measures from the government.
Yesterday, a little known faction of the Pakistani Taliban claimed responsibility for the blast, saying it collaborated with Lashkar-e-Jhangvi (LeJ), which has been behind numerous bloody attacks on Shia Muslims in Pakistan.
They are so frequently targeted they are forced to live in two protected enclaves in the city and are given a daily police escort to the market to stock up on supplies.
The blast occurred in Hazarganji area of Pakistan's Quetta on Friday. "Those commitments must translate now into policies to effectively protect the Hazaras of Quetta, ending more than a decade of bloodshed that has scarred their community". Images from the blast scene showed burnt human flesh, blood-soaked clothes, damaged vehicles and scattered vegetables and fruits.
"I was loading a small truck and I heard a huge bang, and it seemed as if the earth beneath me had shaken and I fell down", worker Irfan Khan said from his hospital bed.
UN Secretary-General Antonio Guterres expressed shock at the Quetta attack and strongly condemned "this cowardly act", UN spokesman Stephane Dujarric said.
Hazara make up about 500,000 of the city's 2.3 million residents.
"The United Nations expresses its full solidarity with the Government of Pakistan in its fight against terrorism and violent extremism", Guterres said.
Balochistan Chief Minister Jam Kamal convened a meeting during which a decision to install closed-circuit television cameras at the Hazarganji market and other public places was decided.
The Islamic State group has claimed responsibility for a suicide bombing at an open-air market in the southwestern Pakistani city of Quetta a day earlier that killed twenty people.
Quetta is the capital of Balochistan, where separatist groups have waged a low-level insurgency.