Those setbacks have well and truly fired him up and it was poor Joao Sousa who felt the full force of Nadal's fury on Monday during a 6-2 6-2 6-2 demolition job in the fourth round.
"I am the world No. 2 and I won 18 grand slams", he joked when asked if the Barty should have been on centre.
Twelve months ago, five-times Wimbledon champion Venus Williams contested her first-round match on Court 2.
When the championships resume on Monday, the men's fourth round will feature more players older than 30 than younger - for the first time in the Open era.
Until this year, world number 66 Humbert had never played a match on grass either as a junior or a professional.
The Swiss reduced Britain's Andy Murray to tears when he beat him in the 2012 final but having set another couple of records on Saturday and armed with what John McEnroe calls "the most lovely shots in tennis" he remains everyone's darling at the All England Club. He was the first to win a game in the third set. but the bickering hope didn't last for long.
But as soon as he lost the opening set in just 17 minutes, we knew top-seed Federer would march into the last eight without barely breaking sweat. Continuing the answer to the question, Rafa feels he deserves the elite court more than Ashleigh Barty.
Berrettini can fire down 140mph serves and owns a whipcrack forehand not unlike Rafael Nadal's.
Berrettini's humiliation was complete when, facing yet another break point in the third, he misjudged the spin on a Federer return, swatted at thin air and fell in a heap on the grass.
Rafael Nadal had plenty to grumble about during the first week of Wimbledon.
He will next play either Sam Querrey or Tennys Sandgren in what will be his 39th appearance in a Grand Slam quarter-final.
Raonic, beaten by Andy Murray in the 2016 final, has made the quarter-finals in the last two years.
Such sentiment seems to follow Federer wherever he goes, with his rival Novak Djokovic often declaring "Roger is the most loved tennis player in the world" - mainly thanks to the strokes that ooze off his racket strings like liquid gold.