The 1,471-kilogram lander is named for Dr Vikram A Sarabhai, the founder of the Indian Space Research Organisation (ISRO).
From there, the vessel is due to land on the lunar surface in the early hours of September 7th IST.
"It will be a terrifying moment as it is something Isro has not done before", said Isro Chairman K Sivan.
Over the next five days the lander will inch toward the Moon surface and try to make a soft landing.
The process of landing Chandrayaan 2 on the moon is very complex since it blasted off at a velocity of 39,240 kilometres per hour, which is nearly 30 times the speed at which sound travels through air. As soon as the lander touches down it should launch the rover, Pragyan, which carried a scientific payload for conducting experiments on the lunar floor. This would be followed by two de-orbit manoeuvres to gradually reduce the altitude at which the Lander Vikram would orbit around the moon and finally achieve an orbit of 36X110 km. It will then release a small solar-powered rover dubbed Pragyan. ISRO said that after the lander's separation on Monday, two deorbit manoeuvres are scheduled for September 3 (9:00-10:00) and September 4 (3:00-4:00) respectively, before the powered decent on September 7.
With the successful separation of both space devices, the focus is now on Vikram's descent.
The module will attempt India's first moon landing on a relatively flat surface on September 7 to study previously discovered water deposits.
After revolving around the Earth's orbit for almost 23 days, the craft began its journey to the moon on August 14.
If India did manage the landing, it would be only the fourth country to do so after the U.S., Russian Federation and China. Inside minutes of the takeoff, the three-stage launcher positioned Chandrayaan 2 on an elliptical orbit that on the closest was some175km from the earth's floor.