The Browns bounced back from a 31-3 shellacking from Seattle's NFC Rival San Francisco on Monday Night Football and had the Hawks reeling, but Seattle settled down and turned the tide.
Seattle failed to convert the two-point attempt after this score and headed into halftime down two points, 20-18, in a game that appears to be the Seahawks for the taking.
Chubb had 122 yards on 20 attempts. Wilson also ran for a 16-yard TD in the first quarter.
But a short Seattle punt gave the Browns the ball right back and Chubb's TD had the crowd rocking.
The Seahawks' defense did a commendable job stopping Cleveland three times from the 1, forcing a turnover on downs and preserving Seattle's five-point lead early in the fourth quarter.
Recovery from Achilles injuries and subsequent surgeries usually come with a timeline of 8 to 12 month meaning the 4-1 Seattle will miss Dissly's presence on the field for at least the rest of this season.
The Browns (2-4) were hurt by their own miscues.
Instead of running the ball, first-year coach Freddie Kitchens called a pass play and Mayfield forced one into the end zone that was behind Jarvis Landry, tipped and intercepted by safety Tedric Thompson.
Cleveland blitzed on the play and Wilson was hit as he threw by linebacker Joe Schobert.
The game began disastrously for Seattle, when Cleveland's Hilliard returned the opening kickoff 74 yards to set up a quick Browns touchdown. Lucky for Seattle, Browns kicker Austin Seibert missed the PAT kicking toward the same end zone where Myers missed a PAT earlier in the game.
That gave Wilson a chance to run the two-minute drill, and the Seahawks QB did what he does, quickly getting Seattle from the Cleveland 12 to Seattle's 22.
A run by C.J. Prosise on the two-point play was stopped.
And when it was over, Seattle had its fourth win this season by four points or less - one win for each of the turnovers committed by the Browns on the day.