That eastward movement means snow, ice and powerful winds will impact post-Thanksgiving travel on Sunday and Monday, the National Weather Service warned.
Though the snow and wind was expected to ease on Sunday, travel remained unsafe, the weather service said.
The National Weather Service reported that blizzard conditions and lakeshore flooding are forecast to continue overnight in Duluth, with additional snowfall of 8 to 16 inches.
The National Weather Service predicted snow starting before 4 p.m. Sunday, changing to freezing rain and sleet during the night and into Monday.
A winter storm warning that began at 9 p.m. Friday will run until noon Sunday from the South Dakota border to Willmar and the Twin Cities and extending east to Eau Claire in Wisconsin.
The companies said they had cancelled 27 flights at O'Hare and two at Midway as people scrambled to get home on the year's busiest travel weekend.
The storm dumped mounds of snow in parts of the West - with California getting 4 feet in Big Bear Lake and Cedar Grove - and is now heading into the Central Plains with blizzard conditions.
As of Saturday afternoon, nearly 600 flights had been canceled and more than 9,600 delayed in the USA, according to FlightAware.
Sunday will be especially disruptive as millions of holiday travelers are expected to head home.
A new system was forecast to develop in the mid-Atlantic on Sunday, moving as a nor'easter into Monday.
Travel interruptions were minimal at Midwestern hubs Saturday morning, with average delays under 15 minutes and only 18 out of over 3,000 flights canceled in the last 24 hours at Chicago O'Hare International Airport, according to the Chicago Department of Aviation.
Due to delays and cancellations, Delta Airlines announced weather waivers for almost two dozen cities in the Northeast for Sunday and Monday, including airports in Boston and the NY area.
Dozens of auto crashes and hundreds of vehicle spinouts occurred Friday night and Saturday morning in the metro area as sleet, snow, rain and wind hit the region.
A 100-mile (160.93-kilometer) section of Interstate 80 in Nebraska and Wyoming closed Saturday morning because of high winds and blowing snow. Several other roads and highways also were closed. The latest road conditions for the state you are calling from can be obtained by calling 5 1 1.
New York, Pennsylvania and New Jersey can expect to see a mix of snow, rain and freezing rain Sunday morning. (Cody Bashore/Arizona Daily Sun via AP) PHOTO: This photo provided by Big Bear Mountain Resort shows a fresh snow fall at Big Bear Mountain Resort in Big Bear Lake, Calif., Friday, Nov. 29, 2019.