Alisson Becker is expected to win the Yashin Award and Jadon Sancho is thought to be the Best Young Player.
Ballon d'Or 2019 Award Ceremony Date and Time, Live Streaming: The Ballon d'Or ceremony will be organised by France Football, where the best men's player and women's player will be adjudged after voting by journalists from around the world.
In doing so, Messi becomes the only player in history to win six Ballon d'Or awards.
Many, however, felt that Spaniards Xavi and Iniesta would have been more worthy winners, having helped their country to World Cup glory in South Africa that summer.
"I hope to continue for a long time", Messi said on Monday in Paris from behind a row of the trophies which honour the world's best soccer player.
Who do you think will win the 2019 Ballon d'Or?
The LaLiga pairing are followed by the cream of the crop from Serie A, with Juventus and AC Milan both boasting eight Ballon d'Or winners to their respective names, while Bundesliga giants Bayern Munich round out the top five with five titles.
Over the course of 2012 Messi netted an astonishing 91 strikes to beat German legend Gerd Muller's previous record of 85 goals in a calendar year, scoring 79 times for Barcelona and 12 more for Argentina. So far this year, Messi has 41 goals in 44 games.
No other player in World Football has dominated their domestic league as much as Messi has and this makes him a strong contender.
It came after a year in which Barca claimed an incredible five-trophy haul, including Champions League and La Liga titles.
Is Messi a favourite to edge ahead of Ronaldo and take his tally to six this year?
"Monday sees the gala for the Ballon d'Or award take place in Paris, France". In 2018-19 the forward scored 51 goals and gave 22 assists.
But even at 32, Messi is continuing to show brilliance week in, week out - which makes him a fitting victor of the award for a record sixth time.