Erdogan established a time-limit for the withdrawal of the Syrian regime forces behind the Turkish observation posts in the Idlib de-escalation zone in northern Syria until the end of February.
Russian Federation and Syrian regime carry out air strikes in Idlib leading to fresh casualties, even as Ankara dispatches more reinforcements to counter regime incursions in ceasefire zone, a war monitor and activists say.
Five Syrian militants of a pro-Iranian group were also killed in the Ezra area of the southern province of Daraa, Observatory head Rami Abdel Rahman said.
Turkish troops are deployed in some of those rebel-held areas to monitor a ceasefire that has been continuously violated by the regime.
He said government forces had "begun to comb districts of Saraqeb and are on the point of taking control of the all of the M5 road", while jihadists had withdrawn to a village north of the town.
Saraqeb has always been an opposition stronghold and it occupies a strategic location on the junction between the M5 highway which links Damascus to Aleppo and the M4 highway which connects Aleppo to Latakia.
Shelling by Syrian government forces killed eight Turkish military personnel on Monday, prompting Turkish forces to strike back.
Russian Federation and Syrian regime carried out air strikes in the Idlib de-escalation zone, northwestern Syria, killing at least 15 civilians, a Syrian civil defence group announced on Thursday, as Turkey sent more reinforcements into the region, setting up new positions in an attempt to stop a regime offensive.
However, in northwestern Syria, the United States has no troops on the ground and thus little leverage on Russian Federation or the Syrian government in asserting its position.
Syria's military command, for its part, has said the presence of Turkish forces was "illegal and a flagrant act of aggression", vowing to respond to any Turkish attack, SANA reported.
Erdogan said this week's clashes amounted to a "new era" in Syria, and that any further attacks would be "responded to in kind".
He said the Turkish military would carry out air and ground operations in Idlib, when necessary.
A Syrian foreign ministry source lashed back at Erdogan's "lies and deceit".
The mass displacement of civilians in Idlib is one of the largest since the start of a conflict that has seen more than half of Syria's pre-war population of 20 million displaced.
Since the eruption of the bloody civil war in Syria in 2011, Turkey has taken in some 3.7 million Syrians who fled their country, making it the world's top refugee-hosting country.
The attacks by the regime forces, Iranian-backed terror groups and Russian strikes stand as the main reasons behind the forced migration.
Speaking at a news conference on Thursday, Ibrahim Kalin said it is not possible for Turkey to accept any proposal of change regarding the de-escalation zone.
Their priority, she told AFP, was to ensure a "regional solution, designed by Moscow and Ankara, as opposed to an worldwide solution parachuted in by the West".