After the match the 28-year-old took to social media to hit back at the abuse, and the referee, with a picture of him sticking his fingers up at the crowd, saying, "I would just like to tell these idiots who come to the stadium to make racist screams. go f*ck yourself".
Porto director of communications Francisco Marques added on his own Twitter account: "Marega was fed up and left the pitch and Porto was forced to make a substitution due to racism".
He was also treated to a yellow card by the referee which is absolutely insane.
In the 71st minute, Porto's coaching staff then ushered Marega away and down the tunnel while he continued his angry exchanges with the Vitoria crowd.
That reaction earned him a yellow card from referee Luis Godinho, before the unsavoury scenes involving his fellow players which followed soon after.
"I hope I will never see you again on a football field".
Marega, a French-born Mali global who had previously played for Vitoria on loan in 2016-17, scored Porto's game victor before the incident. "We deserve respect and what happened was despicable". You are a disgrace!
"Liga Portugal does not agree and never will with acts of racism, xenophobia or intolerance that jeopardise the dignity of footballers or any human beings", said a statement on its website.
"We know the passion that exists at Vitoria and I think that most fans do not recognise themselves in the attitude of other people who insulted Moussa".
Vitoria coach Ivo Vieira said: "I prefer not to speak about a situation without being aware of all the facts".
"FC Porto strongly condemns the racist behaviour this afternoon, which is one of the low moments in the recent history of Portuguese football and will have to be properly penalized". "But if the player was provoked, then he should not have been".