A state of disaster and new restructions will come into play from 6pm tonight, Sunday August 2.
Abattoirs will not be completely closed, but their operations will be affected under tough new workplace rules for essential workers.
Police have been given more powers to enforce the new restrictions.
In a shock move, senior government sources have revealed that the Andrews government is also discussing proposals to allow Bunnings to remain open for trade customers only.
News.com.au understands that the Victoria's Industry department is running projections on the impact of the changes to be announced today on supply chains for red meat, poultry and fish.
It has recorded around 18,000 coronavirus cases and just over 200 Covid-19 deaths, but the recent surge in Victoria has proven hard to contain.
Brett Sutton, Victoria Chief Health Officer said with the introduction of the strict measures, she expects "absolutely that we will see transmission driven down and cases to decrease over time".
Mr Andrews also warned people against panic-buying.
He continued: "But they will be ongoing and they will continue right through the six-week period where we will see a reduction in numbers week on week, as long as people are following the directions that have been laid out".
Over the weekend, Kentucky Fried Chicken confirmed that the shutdowns in Victoria had already forced some stores to limit opening hours.
"We don't know when these measures are going to finish".
The resurgence of the virus in Melbourne has proved to be a major setback for the country, which looked as if it had the outbreak under control.
The new rules will remain in place until at least September 13, and Andrews promised more changes would be coming as well, the BBC reported.
"These are not easy decisions to make", he said.
"We just can't have that".
Millions of tests able to detect the virus within 90 minutes will be rolled out to British hospitals, care homes and laboratories to boost capacity in the coming months, the country's health minister said.
As a result of rising coronavirus cases in Victoria, a curfew has now been introduced between 8pm and 5am every day in Melbourne. Work or study, if you can not work or study from home.
Ubers and taxis are still allowed to operate but Victorians must wear a mask inside the vehicle and must sit in the back seat to comply with social distancing requirements.
Only one person per household is allowed to leave their homes once a day - outside of curfew hours - to pick up essential goods, and they must stay within a 5 kilometer (3.1 miles) radius of their home.