Trump's physician, Dr. Sean Conley, said in a memo shared by White House officials that the president "as a precautionary measure" has "received a single 8 gram dose of Regeneron's polyclonal antibody cocktail".
Press Secretary Kayleigh McEnany told reporters Trump was to be helicoptered to the military hospital after he was given an antibody cocktail created to speed his recovery.
What treatment is he receiving? In 1985, President Ronald Reagan underwent a colonoscopy and briefly turned over power to Vice President George Bush, although he did not explicitly cite the amendment in doing so. Hope was also with Trump the following day when he flew to Duluth, MN for a campaign rally.
"President Trump remains in good spirts, has mild symptoms, and has been working throughout the day", she said.
But he said that, "in consultation with specialists we have elected to initiate Remdesivir therapy", an antiviral medication. "He has completed his first dose and is resting comfortably".
The second journalist was recently part of the out-of-town travel pool on Saturday for the president's trip to Pennsylvania but was briefly at the White House earlier in the day for a COVID-19 test.
Esther Choo, an emergency physician and professor at Oregon Health and Science University, told Al Jazeera that Trump has a number of risk factors for severe COVID-19.
Mr Trump is said to have "mild symptoms". Trump is experiencing a low-grade fever and a cough, news outlets reported Friday.
CNN reports numerous guests for Mr Trump's announcement arrived with masks on, but as the Rose Garden event got underway, masks were virtually nonexistent. One source told the paper he had displayed cold-like symptoms.
During a speech Friday in Grand Rapids, Michigan, Biden said he sent "my prayers for the health and safety of the first lady and the President of the United States". "Unlike the test I took just a few days ago while visiting the White House, yesterday's test came back positive", Senator Lee said on Twitter. Nearly none of the invited guests wore masks, said the reporter, who was not authorized to publicly discuss the situation. "If you are going to do it and maximize the effectiveness of these two interventions you pretty much either do it now or not at all". "LOVE!" Trump tweeted on Saturday.
How did he get it?
Biden tweeted shortly after: "I hope this serves as a reminder: wear a mask, keep social distance, and wash your hands".
"Tonight I tested positive for COVID-19", Conway tweeted Friday evening.
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Kayleigh McEnany released a statement from the president's physician outlining his diagnosis and treatment.
It comes after he and First Lady Melania Trump were forced into self-isolation following positive tests for Covid-19.
"It's not just the folks in the White House or who travel with me who deserve regular testing", Biden said.