The planes took off from BA's London Heathrow hub on Thursday, with their departure live-streamed for aviation enthusiasts and the generations of long-haul travelers who have flown on the hump-backed behemoths.
To commemorate G-CIVB and G-CIVY's final take-off from the airport at 08:30, the airline has arranged a special send off with a unique and rarely seen synchronised dual take off on parallel runways, which will be followed by fly past along the southerly runway by one of the aircraft (G-CIVY in current BA livery) as it bids its home a final farewell.
Their retirement has been brought forward several years because of the financial impact of the pandemic on the airline.
Chief Executive Alex Cruz said it was "a hard day for everybody at British Airways as the aircraft leaves our home at Heathrow for the very last time".
BA said it was already "slowly" phasing out the "fuel-hungry" aircraft in order to help meet a commitment to "net zero by 2050".
The British Overseas Airways Corporation (BOAC), among Bachelor's Degree's predecessors, run its initially 747 London to NY flights in 1971.
The initial airplane, which included 27 First Class and 292 Economy seats, included an upper deck including a lounge.
Once the world's largest operator of the 747, BA has now retired its entire jumbo jet fleet after COVID-19 curtailed most air travel, accelerating the move to more fuel-efficient planes.
In July, Qantas retired its final 747 jumbo. The plane was the largest commercial aircraft in the world, until the arrival of the Airbus A380 in 2007.
The airplane was likewise house to Bachelor's Degree's' really initially flat bed seat, which it presented in 1999. "It is a heart-breaking decision to have to make", Alex Cruz, BA chairman and CEO, said in July following the announcement that the planes would be retired.
"The 747s have played a huge role in our 100-year history, forming the backbone of our fleet for over 50 years".