These include the publication of the preprint and the announcement of AnGes, the partner company of Osaka University in developing this COVID-19 vaccine, in Sept that it had a deal to collaborate with a US company Brickell Biotech, Inc.in preparation for Phase 3 trials once the phase 1/2 goes well.
And now, Brazilian health authority Anvisa revealed that a volunteer in the clinical trial had died from Covid-19 complications. That volunteer's condition wasn't announced until later, when AstraZeneca wrote in an email to CNN that the patient was found to have "an undiagnosed case of multiple sclerosis" and an independent panel concluded the condition was "unrelated to the vaccine".
At a video conference earlier this week, Health Minister Jens Spahn, who himself tested positive for the coronavirus on Wednesday, said Germany's BioNTech was close to getting a vaccine approved, Bild cited participants as saying.
But Doshi raised another important issue - that few or perhaps none of the current vaccine trials appear to be created to find out whether there is a benefit in the elderly, despite their obvious vulnerability to COVID-19.
Veklury is the first treatment for COVID-19 to receive FDA approval, stated the release.
"Pauses occasionally happen. You just rarely hear about them", said Paul Offit, a professor of pediatrics who leads vaccine education at Children's Hospital of Philadelphia and sits on the Vaccines and Related Biological Products Advisory Committee, over email. "And I guess I didn't really know, like, how it applied to the real world until now", she said.
In the case of the UCL and Dokuz Eylul University study, researchers believe that in order to ensure widespread public acceptance as soon as Covid-19 vaccines become available, there should be wider communication of the scientific consensus on the origin of the new coronavirus with the public, as these may help future campaigns targeting Covid-19 vaccine hesitancy.
Those surveyed in an October poll were asked about their willingness to take a COVID-19 vaccine.
Brazil's health authority Anvisa said it had been informed on Monday of the study volunteer's death and had received a partial report from an worldwide committee assessing the trial's safety. Additionally, a small number have developed a serious inflammatory condition linked to the coronavirus.
As a result, the CDC is rolling out a vaccination campaign called "Vaccinate With Confidence" aimed at combating vaccine hesitancy, which may be growing.
The reluctance of Black people to get vaccinated against the virus that causes COVID-19, which has had a disproportionate impact on minorities, is rooted in a broader suspicion toward vaccines in general, according to some experts.
The University of Oxford has not responded to a request for comment.
Assuming Pfizer's shot is proven to work in adults, Frenck said the key will be if the vaccine revs up adolescents' immune systems the same way - without different side effects.