Fortunately for Liverpool, the scans indicated that Gomez had suffered no ligament damage.
The Liverpool defender has since undergone a successful operation on a tendon and, though the his club are reluctant to estimate when he is likely to be back in action, a return before the end of the season can not be ruled out.
Gomez underwent scans to determine the extent of the injury and later had surgery in London on Thursday morning to fix a tendon in his left knee.
It is a devastating blow for Gomez, who missed eight months with an anterior cruciate ligament injury in 2015, as well as Liverpool.
"Gomez will begin a rehabilitation programme with the Reds' medical team immediately, with club staff carefully monitoring his progress".
Here is a list of all Liverpool players now missing due to injury and when they are expected to return, including Joe Gomez, Trent Alexander-Arnold and Thiago Alcantara.
Liverpool's defence is further reeling from the calf injury sustained by Trent Alexander-Arnold in the 1-1 draw against Manchester City last weekend.
Nicol reckons Liverpool must spend big in the January transfer window and says RB Leipzig star Dayot Upamecano is the player he would target.
However, the Reds would most likely have to wait until next summer to sign the 22-year-old Frenchman for around £40m. Schalke's Ozan Kabak is also under consideration, alongside Torino's left-footed Brazilian Bremer. Take our quiz below to find out how much you know about United's number 1's, past and present.