"The club correctly notified PHE, which is standard practice under government and Premier League guidelines".
Telegraph Sport understands the club are in dialogue with the Premier League over the mass outbreak which has forced them to close the training ground since Friday.
Friday night's game with Aston Villa at Villa Park is off, with several Newcastle players self-isolating.
Premier League clubs test players and coaching staff at least twice a week in order to comply with COVID-19 protocols.
Newcastle requested the postponement, believing it would put the club at an unfair disadvantage if players could not train before the Villa match.
Premier League rules state that games should proceed as long as teams have a starting line-up plus three substitutes available, which can include players from the development squads.
With the Magpies' first team now unable to prepare for the match as a group, Newcastle United lodged a request with the Premier League to postpone the fixture at Villa Park, which has been approved by the Premier League Board.
Accordingly, the club is now is working with Public Health England North East (PHE), local health authorities and the Premier League in line with Covid-19 protocols to identify the source of the outbreak and to ensure the risk of further transmission continues to be minimised. Newcastle United would like to thank Aston Villa Football Club for its understanding.
A player who was away during the recent worldwide break also tested positive, but only after he had returned to the club and was around the first-team set-up.
The club's training ground has been closed since the weekend and players have not trained since last Thursday.
They are also relieved that a decision was taken on Sunday to have players and staff re-tested before scrapping Monday's training session on the back of multiple positives.
On Monday, the league confirmed that 10 positive results had been recorded from 1,381 players and staff in the most recent round of testing.
Speaking after Friday's game, Bruce said: "It has been a tough week".