The US set a grim milestone Wednesday by recording 2,804 COVID-19 deaths, according to data compiled by Johns Hopkins University, which was the country's most in a single day and close to the number of people killed on 9/11.
"This most recent surge in Covid-19 cases presents us with an opportunity to work together, again, to reduce its spread and flatten the curve".
The mayor's strongly worded order calls on "all persons living within the City of Los Angeles.to remain in their homes", and to venture out only for prescribed essential reasons.
"The reality is that December, January and February are going to be rough times", Dr Redfield said.
Almost 200,000 new USA cases were reported on Wednesday, with record hospitalizations approaching 100,000 patients.
US deaths from the coronavirus pandemic have surged past 2,000 for two days in a row as the most unsafe season of the year approached, taxing an overwhelmed health care system with USA political leadership in disarray.
On a related note, hospitalizations for COVID-19 in the US increased by more than 1,000 a day at the end of November, data released Tuesday from the Department of Health and Human Services show.
People wearing protective face masks wait in line at a mobile Covid-19 testing unit at Elmhurst Hospital in the Queens borough of New York November 19, 2020. "And if it isn't essential, don't do it", he said during a news conference.
With the national caseload topping 13.6 million, the death toll across the United States rose to 270,003 as of 5:26pm local time (2226 GMT), according to the CSSE data.
The 11 251 new cases announced on Wednesday represent one of the biggest one-day totals recorded by Mexico since the pandemic began.
New York State reported 34,618 fatalities, at the top of the USA state-level death toll list. Illinois' Cook County had 310,722 confirmed cases.
The number of hospitalisations had been steadily growing over the course of last month, setting records almost every day since November 10, and experts worry health care systems will soon feel the strain, CNN reported. The official confirmed US total death toll is now 273,847 as of Wednesday.