"Sheldon was a generous benefactor of charitable causes, especially medical research and Jewish heritage education", Bush continued.
His family confirmed his death in a statement provided by his company, the Las Vegas Sands, and said his death followed complications related to treatment for non-Hodgkin's Lymphoma. The billionaire was known for his strong support for Israel and influence on US-Israel relations over several decades.
In 2004 he took Sands public, growing his net worth to $35.1 billion in March 2019, according to Forbes. "Sheldon battled his way out of a tough Boston neighborhood to build a successful enterprise that loyally employed tens of thousands - and entertained millions".
Trump, 74, released a statement via the White House saying he and First Lady Melania Trump are mourning Adelson's death and they sent their "heartfelt condolences to his wife Miriam, his children and grandchildren".
'Sheldon was the love of my life.
Las Vegas Sands properties include The Venetian Resort and Sands Expo in Las Vegas.
Hotel giant Marriott, health insurer Blue Cross Blue Shield and financial services company American Express said they would stop making donations to Republican lawmakers who tried to halt the certification. Adelson donated $20 million to Trump's 2016 presidential campaign and spoke to Trump frequently after he became president.
He also owns the largest circulating newspaper in the Nevada, the Las Vegas Review-Journal.
With Adelson's death, Netanyahu loses a key US backer who for the last four years had the ear of the American president and worked tirelessly to push Israel's priorities at the White House and in Congress.
Last week it was reported that he would be taking a leave of absence to resume cancer treatment for non-Hodgkin's Lymphoma.