It has slashed interest rates to all-time lows, pumped vast amounts of liquidity into the financial system via cheap loan schemes to banks, and embarked on an asset purchase programme to try and drive up chronically low inflation in the single currency area.
It is feared the unprecedented Brexit vote could damage trade in the region and impact on business confidence, with the establishment of new trade relations potentially years away.
The governing council of the European Central Bank which met today chose to keep the interest rates on the main refinancing operations and the interest rates on the marginal lending facility and the deposit facility unchanged at 0.00 per cent, 0.25 per cent and -0.40 per cent, respectively.
European markets took in their a lack of a hoped-for signal from the ECB about a quick shot of stimulus to handle Brexit but airline shares hit turbulence on Thursday (Jul 21) following a bleak outlook from EasyJet.
To help address the problem, there should be "a public backstop when in times of exceptional circumstances the NPL market is not functioning", Draghi said. "Sufficient data may not be available by the next meeting, pointing towards longer delay", he tweeted.
"Draghi's comments during the press conference did not give any hint on possible next European Central Bank steps".
The ECB generally saw resilience in the market reaction to the United Kingdom departure from the EU.
"Following the U.K.'s referendum, financial markets have weathered the spike in volatility with encouraging resilience", Draghi said.
KEEPING SCORE: France's CAC 40 was down 0.4 percent at 4,362 while Germany's DAX was 0.1 percent lower at 10,133.
Bullion for immediate delivery climbed 0.5 percent to $1,322.38 an ounce by 11:22 a.m.in London, according to Bloomberg generic pricing.
Coupled with the uncertainty over Britain's vote last month to leave the European Union, traders are backing off making any big bets.
United Kingdom budget carrier easyJet fell after reporting a decline in sales while Germany's Lufthansa was also down after issuing a profit warning after the terror attacks hit bookings.
The absence of annual profits guidance "is not reassuring and highlights the wide range of potential outcomes, even at this late stage of the year", said Gerald Khoo, analyst at broker Liberum.
Meanwhile, in the US on Thursday, stocks were mostly mixed as investors kept an eye on corporate earnings and economic data.
Ian Kernohan, economist at Royal London Asset Management, said: "While we think Brexit uncertainty is mainly an issue for the United Kingdom economy, there is also bound to be some knock-on impact on the eurozone". In reaction to Draghi's speech the EURO rises against US Dollar, trading at 1.1050 from 1.10 rate traded in morning session.