"It is a risk, but a calculated one that we must accept, otherwise we'd have to remain in lockdown until a vaccine is developed and we can not afford to do that".
It will also allow travel between the regions - which has so far been tightly restricted - from the same day.
With rates of infection and deaths falling the government said that from June 3 movements to and from overseas can be limited by regional decree "in relation to specific states and territories, in accordance with the principles of adequacy and proportionality to the epidemiological risk".
Germany- whose boundary has to do with a 4-hour drive from Venice via Austria- is advising residents not to traveling overseas for tourist up until a minimum of June15 Officials in bordering France explained that they had actually looked for a collaborated European initiative on boundary openings, suggesting Italy had actually beat the gun.
Earlier this week Serie A clubs selected June 13 as their preferred return date, though government clearance will still be required for play to resume in Italy.
The latest decree is also a boon to Italy's agricultural sector, which relies on roughly 350,000 seasonal workers from overseas. As for the images, he said: "I think in any individual instance you're going to see people doing things that are irresponsible", but says: "That's part of the freedom we have here in America".
"From May 18 retail stores, hairdressers, beauticians, bars, restaurants, pubs, football teams' training sessions and museums will start again", said the country's Prime Minister Giuseppe Conte at a press conference on Saturday.
Serie A clubs have already recalled players back to Italy who had returned to their home countries in order to spend lockdown with their families.
Training will resume on Monday but no decision has been made on when a new season will start after the current season was halted in March due to the coronavirus pandemic.
"From June 15, we can reopen theatres and cinemas".
Gatherings of large groups remain banned.