Mr Graham said China had refused to allow investigators to study how the outbreak started.
Senator Lindsey Graham, a close ally of President Donald Trump, said he was convinced that had it not been for "deception" by China's ruling Communist Party, the virus would not be in the USA, where it has killed more than 80,000 Americans.
"Trump's remarks reflect U.S. resentment towards China and the poor state of the two nations' relationship".
The president's comments follow in the wake of increasingly bellicose statements by USA officials in recent days threatening to sanction, sue or tariff China over its alleged mishandling of the coronavirus crisis.
US President Donald Trump today said he was very disappointed in China over its failure to contain the novel coronavirus, saying the worldwide pandemic cast a pall over his trade deal with Beijing.
"Everything does not depend on a vaccine", Health and Human Services Secretary Alex Azar said on CNN's "State of the Union," echoing language used two days earlier by Trump when he announced an ambitious public-private initiative to achieve widespread inoculation by January. "I will tell you that right now".
Shi Yinhong, a professor of worldwide relations at Renmin University in Beijing, said Trump's remarks reflected the escalating tensions. "Look I am the toughest guy but what happens is they say "okay, we will move to London or we will go to Hong Kong", he said.
"The Chinese said somewhere that they would like to renegotiate the (trade) deal". "I think more likely it got out of control", he said.
"I have a very good relationship, but I just, right now I don't want to speak to him", he told USA media.
Gov. Mike DeWine of OH, a Republican who has sometimes challenged Trump's push for a speedy end to shutdowns, said he hoped to avoid a resurgence in his state as restrictions are eased.
As part of the deal, Beijing agreed to import an additional U.S. $200 billion in United States products over two years including an added USA $32 billion in agricultural goods.
Here's a curious trend when it comes to recent coronavirus developments - some places that are reopening are not seeing a spike in new cases while some that are still closed down are, according to a Reuters report.
Azar's comments come as the mainstream media continues to fan the flames of hysteria after some states, mostly those ran by Republican governors, have chosen to re-open. Whether it came from the lab or came from the bats, it all came from China, and they should have stopped it.
There has been increasing pressure on Trump to take action against China, as many lawmakers and opinion-makers feel that the Covid-19 spread across the world from Wuhan because of Chinese inaction.