Vials with a sticker reading, "COVID-19 / Coronavirus vaccine / Injection only" and a medical syringe are seen in front of a displayed Pfizer logo in this illustration taken October 31, 2020. Grindrod said a fair number of people who receive the vaccine may feel exhausted with some muscle ache for a day or two, while trials have also noted a fever as a less common reaction. The FDA's EUA process involves reviewing key information about efficacy and safety, and the agency says that it has "reviewed thousands of pages of technical information" about the Pfizer/BioNTech vaccine, including materials related to its development and manufacturing, as well as the results of its clinical trials to date.
That said, in the United Kingdom, at least two adverse reactions occurred on the first day of the country's mass vaccination program that began this week, leading regulators in the country to advise that people who have a "significant history" of allergic reactions should avoid receiving the new Pfizer-BioNTech vaccine at this time.
As part of Canada's vaccine rollout, the federal government has announced that anyone who experiences a severe adverse reaction to a COVID-19 vaccine will be eligible for compensation - a first in Canada's history.
Stanford Medicine spokesperson Julie Greicius told The Daily that the number of vaccine doses and timeline for delivery is unknown, although the University is confident vaccinations will begin by the end of next week.
"I think we have to be upfront, without scaring people, that we don't know yet about any potential, rare, long-term adverse events", Moss said.
Lurie also noted the FDA staff identified what he called "disproportionate numbers of Bell's Palsy cases (four in the vaccine groups vs. none in the placebo group)" as a matter that should continue to be monitored, including in the post-marketing phase.
He added: "However, it is important that we put this risk in perspective".
But it's unclear how well the vaccine works in people with HIV and other immune-system disorders. Although side-effects did occur for some participants, nearly all were temporary, and the vaccine has been deemed safe for the general public. She added that the facilities can hold more than 500,000 doses of the Pfizer vaccine and around 300,000 doses of the Moderna vaccine.
"It's kind of freakish seeing society interested in something like this - but how fantastic, too". But two weeks after the first dose, people have good protection against the virus, said Henry. That means vaccinated people might still be able to get infected and pass the virus on, although it would likely be at a much lower rate, said Deborah Fuller, a vaccine expert at the University of Washington. "This includes COVID-19 vaccines that will be rolled out soon". "The upside of that is that these trials moved faster, and it probably moved us toward a vaccine faster... the downside is there's an very bad lot of virus out there..."
The allergic reaction came as a shock to vaccine administrators, but this is expected because all immunization shots have warnings when sold, particularly with allergy and precautions.
If those vaccines are proven to be safe and effective, he said, "there will probably be enough vaccines in the U.S. to vaccinate everyone who wants one" by the summer. "For me, that's where I'm at - I am really excited for my opportunity when it comes up to get the vaccine".